Police say vehicles with cracked windows had to pull over and lined the shoulder of the highway for several hours after the damage that occurred Tuesday at around 11:30pm.
Police Sgt. Jennifer Bell told the St. Louis Post-Dispatch that there were reports of injuries from shattered glass, but details about the injuries were not available Wednesday.
Officers were called to the overpass around 11:30 p.m. and found the teens standing near the railroad tracks on the overpass. Two are age 17 and one is a 16-year-old juvenile.
Authorities said the Missouri Highway Patrol received similar reports of rocks being thrown at vehicles in the same area just days before.