Mandy Murphey is anchor of Fox 2 news at 5 and 9 p.m. Mandy became a full time anchor of FOX 2 News in January 1993, only a year and a half after she joined KTVI FOX 2 as the Contact 2 reporter.

Mandy has been honored with 13 Emmy awards and 4 Edward R. Murrow awards. She prides herself on being an anchor who can report. In 2011, Mandy celebrated her 20th anniversary with KTVI.

She has been promoted numerous charitable organizations over the years. Mandy has served on the board of directors for Share Pregnancy and Infant Loss Support, Inc. She is committed to helping families through the grieving process after the loss of a child to miscarriage, stillbirth or shortly after birth.

Before joining FOX 2, Mandy worked in both radio and television. At WPSD-TV in Paducah, Kentucky she was an anchor, consumer reporter and news producer. Mandy graduated from Murray State University with a Bachelor’s degree in journalism.


Recent Articles
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    FOX Files: Future of Chesterfield Mall

    CHESTERFIELD, MO (KTVI)- Shoppers may have noticed several big name stores closing in Chesterfield Mall.  We talked with the economic director for the city of Chesterfield to find out what was going on with the mall and what its future looks like. Libbey Tucker tells Fox 2’s Mandy Murphey the consumer shopping pie is much bigger now so consumers are spreading their dollars further and wider.  Competition in Chesterfield has had an impact on the mall.  Tucker says when the […]

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    FOX Files: Baby gets 12 blood transfusions before she’s born

    CREVE COEUR, MO (KTVI)-Mandy and Drew Marquis of Jersey County, IL got a devastating phone call from their doctor when Mandy was 9 weeks pregnant.  She had antibodies in her blood stream that would destroy her baby.  She was Rh-negative and her baby was Rh-positive.  The only hope was to get blood to the baby while still in utero. Mercy Hospital gave Mandy 12 intrauterine blood transfusions while she was pregnant and 7 more to the baby after birth. Baby […]

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    St. Louis man writes best seller after surviving burns in a house fire

    ST. LOUIS, MO (KTVI) – John O’Leary wasn’t supposed to live after being burned over 100 percent of his body as a 9-year-old in January of 1987. He wanted to see what it would look like to put gasoline on a piece of cardboard and set it on fire. The gas can exploded. John went through 8 months of excruciating pain, surgeries and therapy. His fingers were amputated. John has now written a book released in March that details how […]

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    Super Tuesday: Clinton, Trump pick up big wins; Cruz takes Texas

    Hillary Clinton and Donald Trump are tightening their grips on the Democratic and Republican presidential nominations while Ted Cruz claimed two states, including Super Tuesday’s biggest prize: Texas. Voters went to the polls in a dozen states Tuesday and CNN so far projects six wins for Clinton and five for Trump. Clinton will take Texas, Georgia, Virginia, Alabama, Tennessee and Arkansas while Trump will win Georgia, Alabama, Massachusetts, Tennessee and Virginia. Bernie Sanders, Clinton’s insurgent Democratic rival, will capture Oklahoma […]

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    FDA mandates new warnings, new data for Essure contraceptive device

    The U.S. Food and Drug Administration said it will require a new “black box warning” label for Essure, an implantable permanent contraceptive device. A black box warning in the labeling of products is “designed to call attention to serious or life-threatening risks,” according to the FDA website. Monday’s announcement comes after more than 5,000 women filed grievances with the FDA between November 2002 and May 2015, complaining of unintended pregnancies, miscarriages, stillbirths and severe pain and bleeding after an Essure […]

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    Children with enlarged tongues come to Mercy Children’s for life-changing surgery

    ST. LOUIS (KTVI) – Kids with a rare syndrome are coming from all over the world to St. Louis’s Mercy Children’s Hospital for their specialized care. The children have Beckwith–Wiedemann syndrome. One in 14,000 children has the disorder, which causes parts of their body to overgrow. Fox 2 News followed a Seattle five-month-old boy whose parents brought him to Mercy for tongue reduction surgery. Without surgery, his teeth and jaw will be malformed as he gets older. Right now, he […]

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    Women share Essure stories as FDA prepares its ruling

    ST. LOUIS (KTVI) – Any day now, the federal government could announce its evaluation of  the popular birth control device Essure. Fox 2 News gathered 10 women in our studios who said they experienced life-altering complications from the non-surgical, permanent birth control procedure. The FDA’s website shows more than 5,000 complaints. Women affected testified last September at hearings in Washington D.C. No recommendations have been made since the hearings, but one is expected by the end of February. A Pennsylvania lawmaker […]

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    Heart Association issues warning on differences in heart attacks for men and women

    (KTVI) – The American Heart Association makes it official issuing a scientific statement on the differences between heart attacks in men and women.  The group stating the differences in risk factors and outcomes may be further pronounced in different ethnic groups.. One cardiologist says one of the biggest issues in treatment between men and women is that women often are not prescribed rehab which could affect their future health.

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    Crimewatch special brings victims’ families together with police

    ST. LOUIS, MO (KTVI) – Families from high profile crimes come together with police chiefs to discuss the growing crime rate in the St. Louis area and what can be done about it.  They shared their pain and experiences so viewers could understand that crime can happen anywhere and at any time. Anchors Mandy Murphey and Rafer Weigel talked with law enforcement about the trend of police officers not initiating as many calls as a result of the Ferguson effect.  […]

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    Soldier shot outside Cardinals game discusses his road to recovery

    ST. LOUIS (KTVI) – The veteran shot and paralyzed after leaving a Cardinals game five weeks ago is learning how to live his life. Chris Sanna’s life changed forever five weeks ago when a gunman shot him as he and his girlfriend were walking to Sanna’s car near the Old Cathedral. “I feel like that guy—that criminal—took my life and flipped it upside down,” Sanna said. The hollow point bullet ricocheted throughout his body, striking his spinal cord, liver, and […]

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    Divorcing couple battles over custody of frozen embryos

    ST. LOUIS, MO (KTVI) – A  divorced couple’s bitter battle over their frozen embryos is going to the court of appeals  This is the first case of it’s kind in Missouri. Our investigation found the signed contracts by couples going through in vitro fertilization are basically worthless. In 2007 Jasha McQueen and Justin Gadberry went through IVF to try to have children. They ended up with four embryos, which are fertilized sperm and eggs. Jasha had two put in and became […]

  • FOX 2 anchor Tom O’Neal retires after 43 years in television news

    ST. LOUIS, MO (KTVI) – Tom O’Neal is retiring on July 3 after 43 years in the television businesses. We look back at his career in St. Louis and the big stories he’s covered in that time. Tom got his first job at KCTV in Kansas city, then moved to KFVS in Cape Girardeau, and then St. Louis, in May of 1974 when he was only 26 years old. He first worked for KSDK Channel 5 and then to KTVI […]