The course of the race will close many roads in the city of St. Louis. Most road closures and detours will be in effect on Sunday between the hours of 6:00am and 2:45pm. Cardinals fans planning to head downtown early for Game 4 of the World Series should be prepared to still deal with some closures.
- Southbound Grand Blvd between Laclede Avenue and Chouteau Avenue
- Tower Grove Avenue from Manchester Avenue to Magnolia Avenue
- Magnolia Avenue from Tower Grove Ave to S. Grand Boulevard
- Russell Blvd from S Grand Blvd to Mississippi Avenue
- Market Street from 18th Street to Compton Avenue
- Forest Park Avenue from Compton Avenue to Kingshighway Blvd.
- Truman Parkway/18th Street from Park Avenue to Chestnut Street
- 1-64 off ramps at 39B and 39A Market Street / 21st Street