The accident happened just after 2 p.m. on Connemara Road near Mexico Road, in front of the El Dorado Estates Mobile Home Park.
Police say a vehicle made a left turn in front of the motorcyclist.
The victim has been identified as James Mainieri, 43, of Foley Missouri.
Accident reconstruction is investigating the accident, but police do not believe drugs or alcohol played a factor in the accident.
The driver of the car was transported to the hospital for treatment of minor injuries.