WASHINGTON COUNTY, Mo. – One child was killed and three other children were seriously injured following a crash Monday morning south of Potosi, Missouri.

The crash happened at 8:30 a.m. on Highway 21, just north of Furnace Creek Road, according to a Missouri State Highway Patrol report.

A 2012 Nissan Murano was traveling southbound when the driver “failed to negotiate a left curve,” went off the right side of the highway, and struck a tree.

Four children were riding in the vehicle with an adult driver at the time of the crash. A 10-year-old girl was pronounced dead at the scene just before 9 a.m. The other children, ages 6, 7, and 8, were seriously injured. They were airlifted to a St. Louis-area hospital.

The children were each wearing their seat belt, the report said.

The 36-year-old driver, who was not wearing a seat belt, was also seriously injured. He was taking the children to school at the time. He was taken by ambulance to a St. Louis-area hospital.

“Anytime someone is seriously injured or—worse—killed, it’s a tragedy for all involved. Not just the people involved in the crash, but the first responders and the community. But when you have children involved, it makes it even more so of a tragedy,” Corporal Dallas Thompson, Missouri State Highway Patrol, said.

“They are so young, so innocent. When you bring it into a small, rural area like we’re in, small school districts that the children go to, it really hits home for a lot of folks: teachers, students, friends, families, and the community.”

The victims are all from Richwoods, Missouri.