ST. LOUIS COUNTY, Mo. — Lanes of southbound Interstate 270 at Manchester Road are closed due to a crash Monday afternoon.

Authorities responded to the crash around 2:55 p.m. MoDOT cameras show traffic backed up for miles. It’s unclear how many vehicles are involved. The road will be closed for at least an hour. Drivers are encouraged to use an alternate route.

FOX 2 will continue to update this story as more information becomes available.