The rig flipped around 1 a.m. Thursday on Interstate 29 near the Interstate 635 interchange.
Police say another tractor-trailer and at least one car hit loose cattle. Police say another driver crashed into a police cruiser. No drivers were injured, but traffic was disrupted for hours as crews cleaned up the mess and rounded up the loose cattle.
Police say several head of cattle had to be euthanized at the scene.
This story has been corrected to reflect the incident occurred near Interstate 635, not Interstate 636.